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The
quantative measurements of the average size by volume (V) hemoglobin content by
weight (W) and hemoglobin concentration (W?V) of the Red Blood cells. Are of
substance aid in diagnosis of various types of anaemias. For the manual
procedure these various are calculated from the total number of Red cells. The
hemoglobin concentration and the hematocrit . these are called red cell indices
, three commonly used red cells indices are.
a)
MCV - Mean Cell Volume.
b)
MCH - Mean Cell hemoglobin Corpuscular
c)
MCHC
– Mean Cell hemoglobin Concentration
MCV - Mean Cell Volume.
The average volume (V) of Red
cells. Because the size of the cell is very small the volume is expressed in
femto liter ( 10 - 15L) or cubic micro meter.
Hct (%) x 10
MCV =
---------------------------
RBC count in Millions
MCH - Mean Cell hemoglobin Corpuscular
The MCH is the average hemoglobin content (by
weight “W”) of a red Cells. Because the amount is very small. The weight is
expressed in pico-gram (pg). the MCH is Calculated by
Hb(g/dl) X 10
MCH =
----------------------------------
RBC count in Millions
MCHC – Mean Cell hemoglobin Concentration
The
MCHC is an expression of the average hemoglobin concentration per unit volume
(100) of packed red cells (W/V). this volume is expressed in g/dl or in % there
are for formula used in the calculation of MCHC and both gives the same
results.
MCH
MCHC =
---------------------- X 100
MCV
Hb(g/dl)
MCHC =
----------------- X 100
Hct (%)